Micropenis in hypogonadotropic hypogonadism: response of the penile androgen receptor to testosterone treatment.

@article{Tietjen1998MicropenisIH,
  title={Micropenis in hypogonadotropic hypogonadism: response of the penile androgen receptor to testosterone treatment.},
  author={D N Tietjen and G Y Uramoto and Donald J. Tindall and Douglas A. Husmann},
  journal={The Journal of urology},
  year={1998},
  volume={160 3 Pt 2},
  pages={1054-7; discussion 1079}
}
PURPOSE We determine whether testosterone therapy alters penile androgen receptor expression within the hypogonadotropic hypogonadal (HPG) micropenis. MATERIALS AND METHODS In protocol 1 a strain of mice with micropenis due to congenital HPG and wild type litter mates were divided into testosterone treated and untreated groups. Treatment was initiated on day 15 of life. On day 90 of life (day 75 of treatment) the mice were sacrificed, and the penises were removed and weighed. In protocol 2… CONTINUE READING