Microparticles and arterial disease.

  title={Microparticles and arterial disease.},
  author={Andrew D. Blann and E Shantsila and Alena Shantsila},
  journal={Seminars in thrombosis and hemostasis},
  volume={35 5},
Microparticles (MPs) are small (diameter <1 microm) fragments that seem likely to represent some form of physiology and/or pathophysiology of the originating cell, be it endothelial, platelet, or leukocyte. Increased numbers of MPs are found in various disease states, including cardiovascular disease, and a considerable weight of literature suggests a value in dissecting the various aspects of cell biology. A role in coagulation has been proposed because there is evidence that some MPs expose… CONTINUE READING