Micronucleus assay in three transplantable mouse tumors.

@article{Gasiska1995MicronucleusAI,
  title={Micronucleus assay in three transplantable mouse tumors.},
  author={Anna Gasińska and L Zabagło and Agnieszka Cichocka},
  journal={Neoplasma},
  year={1995},
  volume={42 5},
  pages={243-8}
}
The cytokinesis-block micronucleus (MN) assay was performed in three mouse tumors: two sarcomas (SaL, MCA) and Lewis lung carcinoma (LLC). To determine the optimal culture durations and cytochalasin B (cyt-B) concentrations to yield the highest proportion of binucleate cells (BC) for each tumor, the influence of the cyt-B concentration (1, 2 and 3 micrograms/ml) and culture duration (24-96) were studied. The amount of BC and the MN frequency was investigated for the different radiation doses (0… CONTINUE READING

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