Micronucleus assay in three transplantable mouse tumors.

  title={Micronucleus assay in three transplantable mouse tumors.},
  author={Anna Gasińska and L Zabagło and Agnieszka Cichocka},
  volume={42 5},
The cytokinesis-block micronucleus (MN) assay was performed in three mouse tumors: two sarcomas (SaL, MCA) and Lewis lung carcinoma (LLC). To determine the optimal culture durations and cytochalasin B (cyt-B) concentrations to yield the highest proportion of binucleate cells (BC) for each tumor, the influence of the cyt-B concentration (1, 2 and 3 micrograms/ml) and culture duration (24-96) were studied. The amount of BC and the MN frequency was investigated for the different radiation doses (0… CONTINUE READING


Publications citing this paper.

Similar Papers

Loading similar papers…