Micronuclei in cytokinesis-blocked lymphocytes of cancer patients following fractionated partial-body radiotherapy.


We applied the cytokinesis-block micronucleus assay to measure chromosome damage in lymphocytes of 11 cancer patients undergoing fractionated partial-body irradiation. Measurements performed before, during and after cessation of radiotherapy showed a dose-related increase in micronucleus frequency in each of the patients studied. When the results for… (More)


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