Microneedle-mediated intradermal delivery of epigallocatechin-3-gallate.

@article{Puri2016MicroneedlemediatedID,
  title={Microneedle-mediated intradermal delivery of epigallocatechin-3-gallate.},
  author={Ashana Puri and Hiep X. Nguyen and Ajay K. Banga},
  journal={International journal of cosmetic science},
  year={2016},
  volume={38 5},
  pages={
          512-23
        }
}
OBJECTIVE Epigallocatechin-3-gallate (EGCG) is the physiologically most active and abundant flavanol, accounting for 50-80% of green tea catechins. It is an anti-inflammatory, antioxidant, chemopreventive and skin photoprotective agent. However, light sensitivity and low permeability of EGCG across the stratum corneum due to its high molecular weight as well as strong binding to the lipid bilayers in the skin make it difficult to be used as a key ingredient in cosmetic products. This study… CONTINUE READING
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