Micromotion of mammalian cells measured electrically.

  title={Micromotion of mammalian cells measured electrically.},
  author={Ivar Giaever and Charles R. Keese},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={88 17},
Motility is a fundamental property of mammalian cells that normally is observed in tissue culture by time lapse microscopy where resolution is limited by the wavelength of light. This paper examines a powerful electrical technique by which cell motion is quantitatively measured at the nanometer level. In this method, the cells are cultured on small evaporated gold electrodes carrying weak ac currents. A large change in the measured electrical impedance of the electrodes is observed when cells… CONTINUE READING
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