Micrometastases in esophagogastric cancer: high detection rate in resected rib segments.

@article{Osullivan1999MicrometastasesIE,
  title={Micrometastases in esophagogastric cancer: high detection rate in resected rib segments.},
  author={Gerald C O'sullivan and Denice Kopchak Sheehan and Andrew E Clarke and Robert Stuart and Jacquie Kelly and M{\'a}ir{\'e}ad Kiely and Tom Walsh and John Kevin Collins and F Shanahan},
  journal={Gastroenterology},
  year={1999},
  volume={116 3},
  pages={543-8}
}
BACKGROUND & AIMS Micrometastases within bone marrow indicate a poor prognosis. We prospectively examined micrometastases in patients undergoing resection of esophagogastric cancers for (1) prevalence in rib marrow; (2) comparative detection rates in rib and iliac crest marrow; (3) responsiveness to neoadjuvant therapy; and (4) viability and tumorigenicity. METHODS In 50 consecutive patients, marrow was obtained before manipulation of the primary tumor. Micrometastatic cells were detected by… CONTINUE READING