Microlesion formation in myocardial cells by high-intensity electric field stimulation.

@article{Jones1987MicrolesionFI,
  title={Microlesion formation in myocardial cells by high-intensity electric field stimulation.},
  author={J. L. Jones and Richard E. Jones and G Balasky},
  journal={The American journal of physiology},
  year={1987},
  volume={253 2 Pt 2},
  pages={H480-6}
}
Arrhythmias, S-T segment changes, immediate refibrillation, and other signs of dysfunction are often observed after clinical and experimental transthoracic defibrillation. In vitro studies suggested that shock-induced dysfunction is induced by sarcolemmal dielectric breakdown accompanied by ionic exchanges through transient, shock-induced microlesions in the sarcolemma. To test this hypothesis, cultured chick embryo myocardial cells were shocked in media containing fluorescein isothiocyanate… CONTINUE READING

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