Microinjections of the dopamine D2 receptor antagonist sulpiride into the medial prefrontal cortex attenuate glucocorticoid-induced impairment of long-term memory retrieval in rats

@article{Pakdel2007MicroinjectionsOT,
  title={Microinjections of the dopamine D2 receptor antagonist sulpiride into the medial prefrontal cortex attenuate glucocorticoid-induced impairment of long-term memory retrieval in rats},
  author={Roghayeh Pakdel and Ali Rashidy-pour},
  journal={Neurobiology of Learning and Memory},
  year={2007},
  volume={87},
  pages={385-390}
}
  • Roghayeh Pakdel, Ali Rashidy-pour
  • Published in
    Neurobiology of Learning and…
    2007
  • Psychology, Medicine
  • We recently reported that blockade of dopamine (DA) D2 receptors attenuated deficits in long-term memory retrieval induced by a systemic injection of corticosterone, but the anatomical sites of such interaction were not known. In this study, we investigated whether the DA D2 receptors located in the medial prefrontal cortex (mPFC) may play a role in the impairing effects of glucocorticoids on the memory retrieval process. Young adult male rats were trained in a one trial inhibitory avoidance… CONTINUE READING

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