Microinjection of salusin-beta into the nucleus tractus solitarii inhibits cardiovascular function by suppressing presympathetic neurons in rostral ventrolateral medulla in rats.

@article{Lu2015MicroinjectionOS,
  title={Microinjection of salusin-beta into the nucleus tractus solitarii inhibits cardiovascular function by suppressing presympathetic neurons in rostral ventrolateral medulla in rats.},
  author={Yan Lu and Y S Wu and Ding Chen and Michael Mei-Hwa Wang and Weizhong Z. Wang and Wen Jun Yuan},
  journal={Physiological research},
  year={2015},
  volume={64 2},
  pages={161-71}
}
Salusin-beta is newly identified bioactive peptide of 20 amino acids, which is widely distributed in hematopoietic system, endocrine system, and the central nervous system (CNS). Although salusin-beta extensively expressed in the CNS, the central cardiovascular functions of salusin-beta are unclear. Our main objective was to determine the cardiovascular effect of microinjection of salusin-beta into the nucleus tractus solitarii (NTS) in anesthetized rats. Bilateral or unilateral microinjection… CONTINUE READING

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