Microinjection of morphine into the nucleus accumbens impairs contextual learning in rats.

@article{Westbrook1997MicroinjectionOM,
  title={Microinjection of morphine into the nucleus accumbens impairs contextual learning in rats.},
  author={Reginald Frederick Westbrook and A J Good and M J Kiernan},
  journal={Behavioral neuroscience},
  year={1997},
  volume={111 5},
  pages={996-1013}
}
A unilateral microinjection of morphine into the amygdala impaired fear conditioning to both a conditioned stimulus (CS) paired with shock and the context where shock occurred, whereas a microinjection of morphine into the nucleus accumbens (NA) spared fear conditioning to the CS but impaired, in a dose-dependent and receptor-specific manner, fear conditioning to the context. Morphine in the NA also spared extinction and latent inhibition of a CS but abolished the context specificity of these… CONTINUE READING

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