Microglial responses to physiological change: Osmotic stress elevates DNA synthesis of neurohypophyseal microglia

@article{Lawson1993MicroglialRT,
  title={Microglial responses to physiological change: Osmotic stress elevates DNA synthesis of neurohypophyseal microglia},
  author={Lisa J Lawson and V Hugh Perry and Saimon Gordon},
  journal={Neuroscience},
  year={1993},
  volume={56},
  pages={929-938}
}
We were interested to discover whether microglia could play a role in the remodelling of the adult CNS or participate in adaptations to physiological rather than pathological changes. We have studied microglia in the neurohypophysis of adult mice since microglia normally interact with neurons in this tissue and the biochemical and anatomical consequences of osmotic stress on the neurohypophysis are well known. In this study, we have examined microglial immuno-phenotype and numbers synthesizing… CONTINUE READING

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