Microglial physiopathology: how to explain the dual role of microglia after acute neural disorders?

@inproceedings{GomesLeal2012MicroglialPH,
  title={Microglial physiopathology: how to explain the dual role of microglia after acute neural disorders?},
  author={Walace Gomes-Leal},
  booktitle={Brain and behavior},
  year={2012}
}
Microglia are the resident macrophages of the central nervous system (CNS). In physiological conditions, resting microglia maintain tissue integrity by scanning the entire CNS parenchyma through stochastic and complex movements of their long processes to identify minor tissue alterations. In pathological conditions, over-activated microglia contribute to neuronal damage by releasing harmful substances, including inflammatory cytokines, reactive oxygen species, and proteinases, but they can… CONTINUE READING
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