Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition

@article{Croisier2005MicroglialII,
  title={Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition},
  author={Emilie Croisier and Linda B. Moran and David T Dexter and Ronald K. B. Pearce and Manuel Gr{\"a}ber},
  journal={Journal of Neuroinflammation},
  year={2005},
  volume={2},
  pages={14 - 14}
}
The role of both microglial activation and alpha-synuclein deposition in Parkinson's disease remain unclear. We have tested the hypothesis that if microglia play a primary role in Parkinson's disease pathogenesis, the microglial "activated" phenotype should be associated with histopathological and/or clinical features of the disease. We have examined microglial MHC class II expression, a widely used marker of microglial activation, the occurrence of CD68-positive phagocytes and alpha-synuclein… CONTINUE READING
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Gwinn-Hardy K: alphaPage 7 of 8 (page number not for citation purposes) Journal of Neuroinflammation

  • AB Singleton, M Farrer, +18 authors J Hardy
  • Science
  • 2005
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Micro - glial inflammation in the parkinsonian substantia nigra : relationship to alpha - synuclein deposition

  • E Croisier, LB Moran, DT Dexter, RK Pearce, MB Graeber
  • J Neuroinflammation
  • 2005

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