Microglial dysfunction in brain aging and Alzheimer's disease.

  title={Microglial dysfunction in brain aging and Alzheimer's disease.},
  author={Kira Irving Mosher and Tony Wyss-Coray},
  journal={Biochemical pharmacology},
  volume={88 4},
Microglia, the immune cells of the central nervous system, have long been a subject of study in the Alzheimer's disease (AD) field due to their dramatic responses to the pathophysiology of the disease. With several large-scale genetic studies in the past year implicating microglial molecules in AD, the potential significance of these cells has become more prominent than ever before. As a disease that is tightly linked to aging, it is perhaps not entirely surprising that microglia of the AD… CONTINUE READING

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