Microglial cell responses to fetal ventral mesencephalic tissue grafting and to active and adoptive immunizations.

@article{Shinoda1996MicroglialCR,
  title={Microglial cell responses to fetal ventral mesencephalic tissue grafting and to active and adoptive immunizations.},
  author={Masaki Shinoda and John L. Hudson and Ingrid Str{\"o}mberg and Barry J. Hoffer and John W. Moorhead and Lars Olson},
  journal={Experimental neurology},
  year={1996},
  volume={141 2},
  pages={173-80}
}
Microglia express cytokines, major histocompatibility (MHC) loci, and several other immunologically important constituents. The aim of this study was to detect immunological responses of microglial cells following allogeneic dopaminergic transplantation using active and adoptive immunizations. Adult inbred Fisher 344 (F344 RT1) rats were unilaterally dopamine (DA) depleted in striatum by injection of 6-hydroxydopamine. The degree of degeneration was assessed by recording the rotational response… CONTINUE READING

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