Microglial M1/M2 polarization and metabolic states.

  title={Microglial M1/M2 polarization and metabolic states.},
  author={Ruben G. Orihuela and Christopher A. McPherson and G Jean Harry},
  journal={British journal of pharmacology},
  volume={173 4},
Microglia are critical nervous system-specific immune cells serving as tissue-resident macrophages influencing brain development, maintenance of the neural environment, response to injury and repair. As influenced by their environment, microglia assume a diversity of phenotypes and retain the capability to shift functions to maintain tissue homeostasis. In comparison with peripheral macrophages, microglia demonstrate similar and unique features with regards to phenotype polarization, allowing… CONTINUE READING
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