Microglial Expression of MHC Class II Increases in Normal Aging of Nonhuman Primates

@article{Sheffield1998MicroglialEO,
  title={Microglial Expression of MHC Class II Increases in Normal Aging of Nonhuman Primates},
  author={Lynette G. Sheffield and Nancy E. J. Berman},
  journal={Neurobiology of Aging},
  year={1998},
  volume={19},
  pages={47-55}
}
The search for factors that influence age-related behavioral and cognitive slowing is ongoing. Because microglia are involved in many neurological disorders, they may also contribute to changes in normal aging. To assess increases in microglial activity, we used an antibody against MHC class II to label microglia in three groups of brains from female Macaca nemestrina: juvenile (2-5 years), young adult (5-11 years), and mature (11-19 years). Image analysis was completed on four white matter and… CONTINUE READING
Highly Cited
This paper has 135 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 76 extracted citations

136 Citations

01020'00'04'09'14'19
Citations per Year
Semantic Scholar estimates that this publication has 136 citations based on the available data.

See our FAQ for additional information.