Microglia play a role in ethanol-induced oxidative stress and apoptosis in developing hypothalamic neurons.

@article{Boyadjieva2013MicrogliaPA,
  title={Microglia play a role in ethanol-induced oxidative stress and apoptosis in developing hypothalamic neurons.},
  author={Nadka I. Boyadjieva and Dipak. K. Sarkar},
  journal={Alcoholism, clinical and experimental research},
  year={2013},
  volume={37 2},
  pages={252-62}
}
BACKGROUND Animals exposed to alcohol during the developmental period develop many physiological and behavioral problems because of neuronal loss in various brain areas including the hypothalamus. Because alcohol exposure is known to induce oxidative stress in developing neurons, we tested whether hypothalamic cells from the fetal brain exposed to ethanol (EtOH) may alter the cell-cell communication between neurons and microglia, thereby leading to increased oxidative stress and the activation… CONTINUE READING

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