Microglia generate external proton and potassium ion gradients utilizing a member of the H/K ATPase family.

@article{Shirihai1998MicrogliaGE,
  title={Microglia generate external proton and potassium ion gradients utilizing a member of the H/K ATPase family.},
  author={Orian S Shirihai and P Smith and K. M. Hammar and Daniel Dagan},
  journal={Glia},
  year={1998},
  volume={23 4},
  pages={339-48}
}
An ion selective electrode in self-referencing mode was employed to detect ionic concentration gradients at the vicinity of microglia isolated from newborn rat brains. At 5 mM extracellular potassium concentration, a gradient of -9.43+/-4.2 microM (n=48) was recorded dissipating over a distance of 10 microm from the outer surface of the cell membrane… CONTINUE READING