Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan

  title={Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan},
  author={Tuan Leng Tay and Catherine B{\'e}chade and Ivana D’Andrea and Marie-Kim St-Pierre and Mathilde S. Henry and Anne Roumier and M E Tremblay},
  journal={Frontiers in Molecular Neuroscience},
Microglia are the predominant immune response cells and professional phagocytes of the central nervous system (CNS) that have been shown to be important for brain development and homeostasis. These cells present a broad spectrum of phenotypes across stages of the lifespan and especially in CNS diseases. Their prevalence in all neurological pathologies makes it pertinent to reexamine their distinct roles during steady-state and disease conditions. A major question in the field is determining… 

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