Microfluidics pushes forward microscopy analysis of actin dynamics

  title={Microfluidics pushes forward microscopy analysis of actin dynamics},
  author={Antoine Jegou and M. Carlier and Guillaume Romet-Lemonne},
Actin filaments, an essential part of the cytoskeleton, drive various cell processes, during which they elongate, disassemble and form different architectures. Over the past 30 years, the study of actin dynamics has relied mainly on bulk solution measurements, which revealed the kinetics and thermodynamics of actin self-assembly at barbed and pointed ends, its control by ATP hydrolysis and its regulation by proteins binding either monomeric actin or filament ends and sides. These measurements… CONTINUE READING