• Corpus ID: 20929627

Microfluidics in Late Adolescence

  title={Microfluidics in Late Adolescence},
  author={George M. Whitesides},
  journal={arXiv: Fluid Dynamics},
  • G. Whitesides
  • Published 10 January 2018
  • Chemistry
  • arXiv: Fluid Dynamics
George Whitesides is a Woodford L. and Ann A. Flowers Professor at Harvard University. In this contribution he describes the development of microfluidic techniques, from the spark that ignited this branch of academic research and its industrial sibling, to potential future application within medicine, security and organic synthesis. The diversity in technologies as well as in applications makes this an intriguing story, but it is in the simplest of materials - paper - that we find some of the… 

Paper microzones as a route to greener analytical chemistry

  • M. Kaljurand
  • Engineering
    Current Opinion in Green and Sustainable Chemistry
  • 2019

A Historical Perspective on Paper Microfluidic Based Point-of-Care Diagnostics

Paper-based microfluidic systems have emerged as one of the most favorable technologies used in many potential applications such as point-of-care diagnostics, flexible electronics, energy storage,

Computer-Aided Design of Microfluidic Circuits.

The review concludes with perspectives on the future of computer-aided microfluidics design, including the introduction of cloud computing, machine learning, new ideation processes, and hybrid optimization.

Unraveling Cancer Metastatic Cascade Using Microfluidics-based Technologies

A comprehensive review of the recent developments in the application of microfluidics-based systems for analysis and understanding of the metastasis cascade from a wider perspective is presented.

Impact of electrode design and voltage waveform on low-potential magnetohydrodynamic fluid actuation

Magnetohydrodynamic actuation of millimetric aqueous sodium chloride droplet samples is achieved using annular copper electrodes and PID control to stay below the electrolysis activation potential.

„Lab on a Chip“

The LOC technology enables laboratory processes to run fully automated in canals in the micrometre range and has the potential of changing the medical practice especially in cases when the central laboratory is not available or is unable to provide results fast enough.

„Lab on a Chip“

ZusammenfassungHintergrundDurch die Miniaturisierung haben sich nicht nur in der Mikroelektronik neue Potenziale ergeben, auch in der Sensorik und Analytik ist durch die Mikrotechnik eine Revolution

Digital biology and chemistry.

While digital formats have been shown to improve the robustness of existing chemistries, it is anticipated that in the future they will enable new chemistries to be used for quantitative measurements, and that digital biology and chemistry will continue to provide further opportunities for measuring biomolecules, understanding natural systems more deeply, and advancing molecular and cellular analysis.

Microfluidics: Fluid physics at the nanoliter scale

Microfabricated integrated circuits revolutionized computation by vastly reducing the space, labor, and time required for calculations. Microfluidic systems hold similar promise for the large-scale

Dynamic pattern formation in a vesicle-generating microfluidic device.

It is shown that a microfluidic device designed to produce reverse micelles can generate complex, ordered patterns as it is continuously operated far from thermodynamic equilibrium.

A microfabricated array of clamps for immobilizing and imaging C. elegans.

The fabrication of a microfluidic device for rapid immobilization of large numbers of live C. elegans for performing morphological analysis, microsurgery, and fluorescence imaging in a high-throughput manner and was possible to immobilize more than 100 worms in less than 15 min.

Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane).

A procedure that makes it possible to design and fabricate microfluidic systems in an elastomeric material poly(dimethylsiloxane) (PDMS) in less than 24 h by fabricating a miniaturized capillary electrophoresis system is described.

Fabrication of microfluidic systems in poly(dimethylsiloxane)

Fabrication of microfluidic devices in poly(dimethylsiloxane) (PDMS) by soft lithography provides faster, less expensive routes to devices that handle aqueous solutions.

Droplet microfluidics for high-throughput biological assays.

Droplets allow sample volumes to be significantly reduced, leading to concomitant reductions in cost, and compartmentalization in droplets increases assay sensitivity by increasing the effective concentration of rare species and decreasing the time required to reach detection thresholds.

Oscillations with uniquely long periods in a microfluidic bubble generator

Understanding spatiotemporal complexity1,2,3 is important to many disciplines, from biology4,5 to finance6. However, because it is seldom possible to achieve complete control over the parameters that

Perfectly monodisperse microbubbling by capillary flow focusing.

The physics of the phenomenon is described and closed expressions for the bubble diameter are obtained as a function of the liquid and gas properties, geometry, and flow parameters, from a large set of experimental results.

Soft robotics for chemists.

This work aims to expand the methods and materials of chemistry and soft-materials science into applications in fully soft robots, and permits solutions of problems in manipulation, locomotion, and navigation, that are different from those used in conventional hard robotics.