• Corpus ID: 46817372

Microfluidics for Biofabrication

@article{Takeuchi2018MicrofluidicsFB,
  title={Microfluidics for Biofabrication},
  author={Shoji Takeuchi},
  journal={arXiv: Fluid Dynamics},
  year={2018}
}
  • S. Takeuchi
  • Published 10 January 2018
  • Engineering
  • arXiv: Fluid Dynamics
Shoji Takeushi is professor in and the Director of the Center for International Research on Integrative Biomedical Systems (CIBiS), Institute of Industrial Science (IIS) at the University of Tokyo. Here he describes his attempts to use inherent function of living materials in engineered systems by reconstructing the biological structure using microfluidic technology. 

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References

SHOWING 1-10 OF 12 REFERENCES

A trap-and-release integrated microfluidic system for dynamic microarray applications

This paper designed, fabricated, and fabricated a dynamic microarrays platform to transport and immobilize particles, infuse reagents, observe the reaction, and retrieve selected particles in a single integrated device through the combination of hydrodynamic and optical approaches.

Lipid bilayer formation by contacting monolayers in a microfluidic device for membrane protein analysis.

An accessible method to form a planar lipid bilayer, simply by contacting two monolayers assembled at the interface between water and organic solvent in a microfluidic chip is described.

Formation of giant lipid vesiclelike compartments from a planar lipid membrane by a pulsed jet flow.

A straightforward method for the preparation of lipid vesicles inspired by forming soap bubbles from a soap film is reported, which allows us to directly encapsulate any molecules or substances of interest into the uniformly sized vesicle in a short time.

Graphene-templated directional growth of an inorganic nanowire.

Inorganic nanowires of gold(I) cyanide can grow directly on pristine graphene, aligning themselves with the zigzag lattice directions of the graphene, indicating that the inorganic material spontaneously binds to the pristine graphene surface.

Highly sensitive and selective odorant sensor using living cells expressing insect olfactory receptors

An odorant sensor whose sensitivity is a few parts per billion in solution and can simultaneously distinguish different types of chemicals that have only a slight difference in double bond isomerism or functional group such as ─OH, ─CHO and ─C(═O)─ is constructed.

Fluid shear triggers microvilli formation via mechanosensitive activation of TRPV6

It is demonstrated that fluid shear stress (FSS), an external mechanical cue, serves as a trigger for microvilli formation in human placental trophoblastic cells and it is revealed that the transient receptor potential, vanilloid family type-6 (TRPV6) calcium ion channel plays a critical role in flow-induced Ca2+ influx and microVilli formation.

Chemical vapor detection using a reconstituted insect olfactory receptor complex.

A bioinspired electrophysiology technique is shown to record the response of reconstituted insect ORs to chemical vapors and the ligand repertoire of the OR of malaria vector mosquito examined by this method differed from that of in vivo studies.

Cell-sized asymmetric lipid vesicles facilitate the investigation of asymmetric membranes.

The formation of asymmetric giant vesicles that include little organic solvent are described, and used to investigate the dynamic responses of lipid molecules in the vesicle membrane to reveal that the lipid asymmetry in bilayer membranes improves the reconstitution ratio of membrane proteins.

Automated Parallel Recordings of Topologically Identified Single Ion Channels

This automated methodology provides a high-throughput drug screening system for the targeting of ion channels and a data-intensive analysis technique for studying ion channel gating mechanisms.