Microfluidics-based diagnostics of infectious diseases in the developing world

  title={Microfluidics-based diagnostics of infectious diseases in the developing world},
  author={Curtis D. Chin and Tassaneewan Laksanasopin and Yuk kee Cheung and David Steinmiller and Vincent Linder and H. Parsa and Jennifer Wang and Hannah C. Moore and Robert V. Rouse and Gisele Umviligihozo and Etienne Karita and Lambert Mwambarangwe and Sarah L. Braunstein and Janneke van de Wijgert and Ruben Sahabo and Jessica E. Justman and Wafaa M El-Sadr and Samuel K. Sia},
  journal={Nature Medicine},
One of the great challenges in science and engineering today is to develop technologies to improve the health of people in the poorest regions of the world. Here we integrated new procedures for manufacturing, fluid handling and signal detection in microfluidics into a single, easy-to-use point-of-care (POC) assay that faithfully replicates all steps of ELISA, at a lower total material cost. We performed this 'mChip' assay in Rwanda on hundreds of locally collected human samples. The chip had… CONTINUE READING
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