Microfluidics-based diagnostics of infectious diseases in the developing world

@article{Chin2011MicrofluidicsbasedDO,
  title={Microfluidics-based diagnostics of infectious diseases in the developing world},
  author={Curtis D. Chin and Tassaneewan Laksanasopin and Yuk kee Cheung and David Steinmiller and Vincent Linder and H. Parsa and Jennifer Wang and Hannah C. Moore and Robert V. Rouse and Gisele Umviligihozo and Etienne Karita and Lambert Mwambarangwe and Sarah L. Braunstein and Janneke van de Wijgert and Ruben Sahabo and Jessica E. Justman and Wafaa M El-Sadr and Samuel K. Sia},
  journal={Nature Medicine},
  year={2011},
  volume={17},
  pages={1015-1019}
}
One of the great challenges in science and engineering today is to develop technologies to improve the health of people in the poorest regions of the world. Here we integrated new procedures for manufacturing, fluid handling and signal detection in microfluidics into a single, easy-to-use point-of-care (POC) assay that faithfully replicates all steps of ELISA, at a lower total material cost. We performed this 'mChip' assay in Rwanda on hundreds of locally collected human samples. The chip had… CONTINUE READING
Highly Cited
This paper has 264 citations. REVIEW CITATIONS
Related Discussions
This paper has been referenced on Twitter 40 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 135 extracted citations

A smartphone dongle for diagnosis of infectious diseases at the point of care

Science Translational Medicine • 2015
View 7 Excerpts
Highly Influenced

Toward Integrated Molecular Diagnostic System ($i$ MDx): Principles and Applications

IEEE Transactions on Biomedical Engineering • 2014
View 4 Excerpts
Method Support
Highly Influenced

265 Citations

0204060'13'15'17'19
Citations per Year
Semantic Scholar estimates that this publication has 265 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 34 references

Microfluidic point-of-care diagnostics for resource-poor environments

2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society • 2009

The evaluation of a rapid in situ HIV confirmation test in a programme with a high failure rate of the WHO HIV two-test diagnostic algorithm

Klarkowski, D.B
PLOS One 4, • 2009