Microfluidic reactor for continuous cultivation of Saccharomyces cerevisiae.

  title={Microfluidic reactor for continuous cultivation of Saccharomyces cerevisiae.},
  author={Astrid Edlich and Veronika Magdanz and Detlev Rasch and Stefanie Demming and Shobeir Aliasghar Zadeh and R. Segura and Christian K{\"a}hler and Rolf Radespiel and Stephanus B{\"u}ttgenbach and Ezequiel Franco-Lara and Rainer Krull},
  journal={Biotechnology progress},
  volume={26 5},
A diffusion-based microreactor system operated with a reaction volume of 8 μL is presented and characterized to intensify the process understanding in microscale cultivations. Its potential as screening tool for biological processes is evaluated. The advantage of the designed microbioreactor is the use for the continuous cultivation mode by integrating online measurement technique for dissolved oxygen (DO) and optical density (OD). A further advantage is the broaden application for biological… CONTINUE READING