Microfluidic packaging of suspended microchannel resonators for biomolecular detection

@article{Burg2005MicrofluidicPO,
  title={Microfluidic packaging of suspended microchannel resonators for biomolecular detection},
  author={T. P. Burg and S. R. Manalis},
  journal={2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology},
  year={2005},
  pages={264-267}
}
Microfabricated transducers enable the label-free detection of biomolecules in nanoliter size samples. We have recently developed a new resonant micromechanical mass sensor that is exceptionally well suited for the detection of biomolecular interactions in a microfluidic framework. Our approach completely eliminates viscous damping by confining the fluid to the inside of a hollow resonator of less than 0.1 nL volume. However, previously we had not been able to integrate all device components… CONTINUE READING

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