Microfluidic mixing and the formation of nanoscale lipid vesicles.

  title={Microfluidic mixing and the formation of nanoscale lipid vesicles.},
  author={Andreas Jahn and Samuel M. Stavis and Jennifer S Hong and Wyatt N. Vreeland and Don L. DeVoe and Michael Gaitan},
  journal={ACS nano},
  volume={4 4},
We investigate the formation of unilamellar lipid vesicles (liposomes) with diameters of tens of nanometers by controlled microfluidic mixing and nanoparticle determination (COMMAND). Our study includes liposome synthesis experiments and numerical modeling of our microfluidic implementation of the batch solvent injection method. We consider microfluidic liposome formation from the perspective of fluid interfaces and convective-diffusive mixing, as we find that bulk fluid flow parameters… CONTINUE READING
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