Microfluidic devices for measuring gene network dynamics in single cells

  title={Microfluidic devices for measuring gene network dynamics in single cells},
  author={Matthew R. Bennett and Jeff Hasty},
  journal={Nature Reviews Genetics},
The dynamics governing gene regulation have an important role in determining the phenotype of a cell or organism. From processing extracellular signals to generating internal rhythms, gene networks are central to many time-dependent cellular processes. Recent technological advances now make it possible to track the dynamics of gene networks in single cells under various environmental conditions using microfluidic 'lab-on-a-chip' devices, and researchers are using these new techniques to analyse… CONTINUE READING

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Dynamic analysis of MAPK signaling using a high - throughput microfluidic single - cell imaging platform

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