Microfluidic cytometer based on dual photodiode detection for cell size and deformability analysis.

  title={Microfluidic cytometer based on dual photodiode detection for cell size and deformability analysis.},
  author={Qin-Qin Ji and Guan-Sheng Du and Martijn J van Uden and Qun Fang and Jaap M J den Toonder},
Cellular mechanical properties play an important role in disease diagnosis. Distinguishing cells based on their mechanical properties provides a potential method for label-free diagnosis. In this work, a convenient and low-cost microfluidic cytometer was developed to study cell mechanical properties and cell size based on the change of transmission intensity, using a low-cost commercial laser as a light source and two photodiodes as detectors. The cells pass through a narrow microchannel with a… CONTINUE READING
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