Microfluidic compartmentalized co-culture platform for CNS axon myelination research.

@article{Park2009MicrofluidicCC,
  title={Microfluidic compartmentalized co-culture platform for CNS axon myelination research.},
  author={Jaewon Park and Hisami Koito and Jianrong Li and Arum Han},
  journal={Biomedical microdevices},
  year={2009},
  volume={11 6},
  pages={1145-53}
}
This paper presents a circular microfluidic compartmentalized co-culture platform that can be used for central nervous system (CNS) axon myelination research. The microfluidic platform is composed of a soma compartment and an axon/glia compartment connected through arrays of axon-guiding microchannels. Myelin-producing glia, oligodendrocytes (OLs), placed in the axon/glia compartment, interact with only axons but not with neuronal somata confined to the soma compartment, reminiscent to in vivo… CONTINUE READING

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