• Corpus ID: 248572332

Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks

@inproceedings{Sato2022MicrofluidicCE,
  title={Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks},
  author={Y Sato and Hideaki Yamamoto and Hideyuki Kato and Takashi Tanii and Shigeo Sato and Ayumi Hirano-Iwata},
  year={2022}
}
Neuronal networks in dissociated culture combined with cell engineering technology offer a pivotal platform to constructively explore the relationship between structure and function in living neuronal networks. Here, we fabricated defined neuronal networks possessing a modular architecture on high-density microelectrode arrays (HD-MEAs), a state-of-the-art electrophysiological tool for recording neural activity with high spatial and temporal resolutions. We first established a surface coating… 

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