Microfabricated analytical systems for integrated cancer cytomics

@article{Wlodkowic2010MicrofabricatedAS,
  title={Microfabricated analytical systems for integrated cancer cytomics},
  author={Donald Wlodkowic and Jonathan M. Cooper},
  journal={Analytical and Bioanalytical Chemistry},
  year={2010},
  volume={398},
  pages={193-209}
}
Tracking and understanding cell-to-cell variability is fundamental for systems biology, cytomics and computational modelling that aids e.g. anti-cancer drug discovery. Limitations of conventional cell-based techniques, such as flow cytometry and single cell imaging, however, make the high-throughput dynamic analysis on cellular and subcellular processes tedious and exceedingly expensive. The development of microfluidic lab-on-a-chip technologies is one of the most innovative and cost-effective… CONTINUE READING

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