Microexons on the brain

  title={Microexons on the brain},
  author={B Laflamme},
  journal={Nature Genetics},
Autism spectrum disorder (ASD) is genetically heterogeneous, with most ASD-associated variants accounting for very few cases. Michael Snyder and colleagues used a systems biology approach to identify common pathways dysregulated in ASD (Mol. Syst. Biol. 10, 774, 2014). Highly interacting modules were extracted from a protein interaction network. Two modules were significantly enriched for known ASD susceptibility genes, and one contained multiple genes involved in synaptic transmission. Whole… CONTINUE READING
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