Microenvironmental adaptation of experimental tumours to chronic vs acute hypoxia

@article{Thews2004MicroenvironmentalAO,
  title={Microenvironmental adaptation of experimental tumours to chronic vs acute hypoxia},
  author={Oliver Thews and Tanja Wolloscheck and Wolfgang Dillenburg and Stephan Kraus and Debra K. Kelleher and Moritz Anton Konerding and Peter Vaupel},
  journal={British Journal of Cancer},
  year={2004},
  volume={91},
  pages={1181 - 1189}
}
This study investigated long-term microenvironmental responses (oxygenation, perfusion, metabolic status, proliferation, vascular endothelial growth factor (VEGF) expression and vascularisation) to chronic hypoxia in experimental tumours. Experiments were performed using s.c.-implanted DS-sarcomas in rats. In order to induce more pronounced tumour hypoxia, one group of animals was housed in a hypoxic atmosphere (8% O2) for the whole period of tumour growth (chronic hypoxia). A second group was… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Impact of hypoxia on the metastatic potential of human prostate cancer cells.

International journal of radiation oncology, biology, physics • 2011
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 65 references

Hypoxia-inducible factor 1 regulates vascular endothelial growth factor expression in human pancreatic cancer

P Buchler, HA Reber, +5 authors OJ Hines
Pancreas 26: • 2003
View 1 Excerpt

Treatment of head and neck cancer with CHART and nimorazole: phase II study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology • 2003
View 1 Excerpt

Effect of hypoxia on human seminoma cells.

International journal of oncology • 2002
View 1 Excerpt

Similar Papers

Loading similar papers…