Microenvironment 3867 , a Synthetic Compound , Inhibits the Migration and sion of Ovarian Carcinoma Cells through Downregulation R atty Acid Synthase and Focal Adhesion Kinase

@inproceedings{Selvendiran2010Microenvironment3,
  title={Microenvironment 3867 , a Synthetic Compound , Inhibits the Migration and sion of Ovarian Carcinoma Cells through Downregulation R atty Acid Synthase and Focal Adhesion Kinase},
  author={paiyah Selvendiran and Shabnam Ahmed and Alex Dayton and Yazhini Ravi and Muthulakshmi L Kuppusamy and Bratasz and Brian K. Rivera and T{\'a}m{\'a}s K{\'a}l{\'a}i and K{\'a}lm{\'a}n Hideg and Periannan Kuppusamy},
  year={2010}
}
ownload y acid synthase (FAS) and focal adhesion kinase (FAK), which are overexpressed in a variety of human lial tumors, play a key role in the migration and invasion of cancer cells. Hence, strategies targeted at ting the FAS/FAK proteins may have therapeutic potential for cancer treatment. The goal of the present was to determine the effect of HO-3867, a synthetic compound, on the migratory ability of ovarian cells and to understand the mechanistic pathways including the involvement of FAS… CONTINUE READING