Microdissection is essential for gene expression profiling of clinically resected cancer tissues.

@article{Sugiyama2002MicrodissectionIE,
  title={Microdissection is essential for gene expression profiling of clinically resected cancer tissues.},
  author={Yuko Sugiyama and Kazuo Sugiyama and Yasuo Hirai and Futoshi Akiyama and Katsuhiko Hasumi},
  journal={American journal of clinical pathology},
  year={2002},
  volume={117 1},
  pages={109-16}
}
The gene expression array method enables us to achieve expression profiling with thousands of genes. Clinically resected bulk cancer tissues, however, contain not only cancer cells but also stromal cells, which may affect gene expression profiling and hamper accurate analysis of the cancer cells per se. Therefore, a procedure for dissecting specific cells, such as laser capture microdissection, is neededfor the clinical application of a gene expression array. There has been no study actually… CONTINUE READING