Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors.

@article{Nash1991MicrodialysisSO,
  title={Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors.},
  author={J. Frank Nash and Joshua Brodkin},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1991},
  volume={259 2},
  pages={820-5}
}
The effect of dopamine (DA) and serotonin (5-HT) uptake inhibitors on 3,4-methylenedioxymethamphetamine (MDMA)-induced increase in DA efflux was studied using in vivo microdialysis. MDMA was infused directly into the anterolateral striatum via the dialysis probe. The local administration of MDMA produced a dose- and time-dependent increase in the extracellular concentration of DA in the striatum. Peripheral administration of the DA uptake blockers, mazindol (5 mg/kg, i.p.) or GBR 12909 (10 mg… CONTINUE READING

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The effect of dopamine ( DA ) and serotonin ( 5-HT ) uptake inhibitors on 3,4-methylenedioxymethamphetamine ( MDMA)-induced increase in DA efflux was studied using in vivo microdialysis .
The effect of dopamine ( DA ) and serotonin ( 5-HT ) uptake inhibitors on 3,4-methylenedioxymethamphetamine ( MDMA)-induced increase in DA efflux was studied using in vivo microdialysis .
The effect of dopamine ( DA ) and serotonin ( 5-HT ) uptake inhibitors on 3,4-methylenedioxymethamphetamine ( MDMA)-induced increase in DA efflux was studied using in vivo microdialysis .
The effect of dopamine ( DA ) and serotonin ( 5-HT ) uptake inhibitors on 3,4-methylenedioxymethamphetamine ( MDMA)-induced increase in DA efflux was studied using in vivo microdialysis .
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