Microdeletion syndromes disclose replication timing alterations of genes unrelated to the missing DNA

Abstract

The temporal order of allelic replication is interrelated to the epigenomic profile. A significant epigenetic marker is the asynchronous replication of monoallelically-expressed genes versus the synchronous replication of biallelically-expressed genes. The present study sought to determine whether a microdeletion in the genome affects epigenetic profiles of… (More)
DOI: 10.1186/1755-8166-2-11

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