[Genomic instability in the brain: etiology, pathogenesis and new biological markers of psychiatric disorders].
- A S Tiganov, Iu B Iurov, S G Vorsanova, I Iu Iurov
- Vestnik Rossiiskoi akademii meditsinskikh nauk
- 2012
Microdeletion syndromes disclose replication timing alterations of genes unrelated to the missing DNA
- Published 2009 in Molecular Cytogenetics
Abstract
The temporal order of allelic replication is interrelated to the epigenomic profile. A significant epigenetic marker is the asynchronous replication of monoallelically-expressed genes versus the synchronous replication of biallelically-expressed genes. The present study sought to determine whether a microdeletion in the genome affects epigenetic profiles of… (More)