Microdeletion 4p16.3 in three unrelated patients with Wolf-Hirschhorn syndrome

@article{Dufke2000Microdeletion4I,
  title={Microdeletion 4p16.3 in three unrelated patients with Wolf-Hirschhorn syndrome},
  author={Andreas Dufke and J{\"o}rg Seidel and Martin Sch{\"o}ning and Marion D{\"o}bler-Neumann and Christina Kelbova and Thomas Liehr and Volkmar Beensen and Claudia Backsch and Ute Klein-Vogler and Herbert Enders},
  journal={Cytogenetic and Genome Research},
  year={2000},
  volume={91},
  pages={81 - 84}
}
Wolf-Hirschhorn syndrome (WHS) is a multiple malformation syndrome caused by partial monosomy of 4p16.3. Pitt-Rogers-Danks syndrome, first thought to be a distinct entity, is a similar condition associated with a microdeletion overlapping the WHS critical region. In this paper we evaluate three WHS patients showing a microdeletion of 4p and remarkable development with respect to the clinical spectrum of WHS. 

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