Microdamage and osteocyte-lacuna strain in bone: a microstructural finite element analysis.

  title={Microdamage and osteocyte-lacuna strain in bone: a microstructural finite element analysis.},
  author={Patrick J. Prendergast and Rik Huiskes},
  journal={Journal of biomechanical engineering},
  volume={118 2},
Damage accumulation in living tissues occurs when the rate of damage formation is greater than the rate of damage repair. For very large increases in the loading rate of bones, this can result in "stress fractures" due to the growth and coalescence of fatigue related microdamage. At lower increases of loading rates, the damage accumulation process is halted because there is time for adaptive bone-remodeling to occur in response to the new load. However, it is not known if there is a… CONTINUE READING


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