Microcystin analysis in human sera and liver from human fatalities in Caruaru, Brazil 1996.

@article{Yuan2006MicrocystinAI,
  title={Microcystin analysis in human sera and liver from human fatalities in Caruaru, Brazil 1996.},
  author={Moucun Yuan and Wayne W. Carmichael and Elizabeth D. Hilborn},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2006},
  volume={48 6},
  pages={
          627-40
        }
}
In 1996, an extensive exposure of Brazilian hemodialysis patients at a dialysis center, using a municipal water supply water contaminated with cyanotoxins, provided the first evidence for acute lethal human poisoning from the cyclic peptide hepatotoxins called microcystins. During this outbreak, 100 of 131 patients developed acute liver failure and 52 of these victims were confirmed to have been exposed to lethal levels of microcystins. Detection and quantitation of microcystins in these… CONTINUE READING

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