Microcirculatory dysfunction and resuscitation: why, when, and how.

  title={Microcirculatory dysfunction and resuscitation: why, when, and how.},
  author={John P. Moore and Alex Dyson and Mervyn Singer and John F. Fraser},
  journal={British journal of anaesthesia},
  volume={115 3},
Cardiovascular resuscitation is a cornerstone of critical care practice. Experimental advances have increased our understanding of the role of the microcirculation in shock states and the development of multi-organ failure. Strategies that target the microcirculation in such conditions, while theoretically appealing, have not yet been shown to impact upon clinical outcomes. This review outlines the current understanding of microcirculatory dysfunction in septic, cardiogenic, and hypovolaemic… CONTINUE READING
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