Microchip-induced tumors in laboratory rodents and dogs: A review of the literature 1990–2006

@article{Albrecht2010MicrochipinducedTI,
  title={Microchip-induced tumors in laboratory rodents and dogs: A review of the literature 1990–2006},
  author={Katherine Albrecht},
  journal={2010 IEEE International Symposium on Technology and Society},
  year={2010},
  pages={337-349}
}
  • Katherine Albrecht
  • Published 2010
  • Computer Science, Engineering
  • 2010 IEEE International Symposium on Technology and Society
This paper reviews literature published in oncology and toxicology journals between 1990 and 2006 addressing the effects of implanted radio-frequency (RFID) microchips on laboratory rodents and dogs. Eleven articles were reviewed in all, with eight investigating mice and rats, and three investigating dogs. In all but three of the articles, researchers observed that malignant sarcomas and other cancers formed around or adjacent to the implanted microchips. The tumors developed in both… Expand
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TLDR
Tumors surrounding implanted microchip animal identification devices were noted in two separate chronic toxicity/oncogenicity studies using F344 rats, and the mechanism of carcinogenicity appeared to be that of foreign-body induced tumorigenesis. Expand
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TLDR
During a 26-wk study to assess the potential carcinogenicity of oxymetholone using p-cresidine as a positive control, glass/ polypropylene microchips were subcutaneously implanted into male and female p53+/- mice, revealing 18 of 177 animals had a subcutaneous histologically malignant sarcoma. Expand
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TLDR
Two subcutaneous tumours associated with microchip were collected from three carcinogenicity B6C3F1 mice studies and appear to have similar histologic-type lineage and designation as sarcomas not otherwise specified (NOS) with a large myofibroblastic component appears today to be more appropriate and it is likely to clarify them in the future with the emergence of new markers. Expand
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TLDR
An 11-year-old male, mixed breed dog was examined by the referring veterinarian for a subcutaneous mass, located in the lateral region of the neck, craniodorsally to the top of the left shoulder blade, which appeared dark reddish due to haemorrhages and abundant vascularisation; it had a bumpy surface and was friable on sectioning. Expand
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TLDR
A 9-year-old, male French Bulldog was examined for a subcutaneous mass suggestive of a malignant mesenchymal neoplasm, which was confirmed as a high-grade infiltrative fibrosarcoma, with multifocal necrosis and peripheral lymphoid aggregates. Expand
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TLDR
A survey of preweaning mortality in pigs and specificity of the precipitin test for their detection with relation to streptococcal antigens of groups P and U and Corynebacterium pyogenes. Expand
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TLDR
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TLDR
A two-year study to determine the stability of and tissue reaction to a microchip glass-sealed device implanted in subcutaneous tissue of mice was conducted, indicating that the capsule around the implants was thin and composed of fibrocytes and mature collagen fibers, with minimal to mild inflammation and occasional granulomatous reaction. Expand
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