Microchimeric cells in systemic lupus erythematosus: targets or innocent bystanders?

@article{Stevens2006MicrochimericCI,
  title={Microchimeric cells in systemic lupus erythematosus: targets or innocent bystanders?},
  author={A. Michal Stevens},
  journal={Lupus},
  year={2006},
  volume={15 11},
  pages={820-6}
}
During pregnancy maternal and fetal cells commute back and forth leading to fetal microchimerism in the mother and maternal microchimerism in the child that can persist for years after the birth. Chimeric fetal and maternal cells can be hematopoietic or can differentiate into somatic cells in multiple organs, potentially acting as targets for 'autoimmunity' and so have been implicated in the pathogenesis of autoimmune diseases that resemble graft-versus-host disease after stem cell… CONTINUE READING