Corpus ID: 44950485

Microcephaly: general considerations and aids to nosology.

@article{Opitz1990MicrocephalyGC,
  title={Microcephaly: general considerations and aids to nosology.},
  author={J. Opitz and M. Holt},
  journal={Journal of craniofacial genetics and developmental biology},
  year={1990},
  volume={10 2},
  pages={
          175-204
        }
}
  • J. Opitz, M. Holt
  • Published 1990
  • Medicine
  • Journal of craniofacial genetics and developmental biology
  • Microcephaly is defined as an occipito-frontal head circumference (OFC) 2 or more standard deviations below the mean for age and sex using the new Roche et al. [Pediatrics 1987;79:706-712] charts, and corrected for parental OFC by the method of Weaver and Christian [J Pediatr 1980;96:990-994]. "Relative" microcephaly, i.e., a small head on a small child, may be associated with a much better intellectual prognosis than absolute microcephaly, although the average IQ of children with absolute… CONTINUE READING
    84 Citations

    Topics from this paper

    Nonsyndromic microcephaly: an overview.
    • 17
    Diagnostic approach to fetal microcephaly.
    • Z. Leibovitz, T. Lerman‐Sagie
    • Medicine
    • European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
    • 2018
    • 1
    New guidance is needed on diagnosing microcephaly in severely malnourished children
    A Case-Control Etiologic Study of Microcephaly
    • 11
    Autosomal dominant microcephaly with normal intelligence, short palpebral fissures, and digital anomalies.
    • 8
    • PDF