Corpus ID: 44950485

Microcephaly: general considerations and aids to nosology.

  title={Microcephaly: general considerations and aids to nosology.},
  author={J. Opitz and M. Holt},
  journal={Journal of craniofacial genetics and developmental biology},
  volume={10 2},
  • J. Opitz, M. Holt
  • Published 1990
  • Medicine
  • Journal of craniofacial genetics and developmental biology
  • Microcephaly is defined as an occipito-frontal head circumference (OFC) 2 or more standard deviations below the mean for age and sex using the new Roche et al. [Pediatrics 1987;79:706-712] charts, and corrected for parental OFC by the method of Weaver and Christian [J Pediatr 1980;96:990-994]. "Relative" microcephaly, i.e., a small head on a small child, may be associated with a much better intellectual prognosis than absolute microcephaly, although the average IQ of children with absolute… CONTINUE READING
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