Microcarrier suspension cultures for high-density expansion and differentiation of human pluripotent stem cells to neural progenitor cells.

@article{Bardy2013MicrocarrierSC,
  title={Microcarrier suspension cultures for high-density expansion and differentiation of human pluripotent stem cells to neural progenitor cells.},
  author={Jo'an Bardy and Allen Kuan-Liang Chen and Yu Ming Lim and Selena Meiyun Wu and Shunhui Wei and Han Weiping and Ken J. Chan and Shaul Reuveny and Steve Kah-Weng Oh},
  journal={Tissue engineering. Part C, Methods},
  year={2013},
  volume={19 2},
  pages={
          166-80
        }
}
Neural progenitor cells (NPCs) derived from human induced pluripotent stem cells (hiPSCs) can be differentiated to neural cells that model neurodegenerative diseases and be used in the screening of potential drugs to ameliorate the disease phenotype. Traditionally, NPCs are produced in 2D cultures, in low yields, using a laborious process that includes generation of embryonic bodies, plating, and colony selections. To simplify the process and generate large numbers of hiPSC-derived NPCs, we… CONTINUE READING
BETA
Tweets
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
SHOWING 1-10 OF 33 CITATIONS

Similar Papers

Loading similar papers…