Microbubbles as novel pressure-sensitive MR contrast agents.

  title={Microbubbles as novel pressure-sensitive MR contrast agents.},
  author={Andrew L. Alexander and Thomas McCreery and Terrence R. Barrette and Arthur F. Gmitro and Evan C. Unger},
  journal={Magnetic resonance in medicine},
  volume={35 6},
Magnetic resonance imaging contrast agents that are sensitive to pressure would be useful for evaluating cardiovascular function. One such potential contrast agent consists of gas-filled liposome microbubbles. The magnetic susceptibility of the microbubbles locally perturb the static magnetic field, which influences the transverse-relaxation properties of the surrounding medium. Changes in the pressure alter the bubble dimensions, which affects the magnetic field perturbations and, hence, the… CONTINUE READING


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