Microbiota transplantation restores normal fecal bile acid composition in recurrent Clostridium difficile infection.

Abstract

Fecal microbiota transplantation (FMT) has emerged as a highly effective therapy for refractory, recurrent Clostridium difficile infection (CDI), which develops following antibiotic treatments. Intestinal microbiota play a critical role in the metabolism of bile acids in the colon, which in turn have major effects on the lifecycle of C. difficile bacteria… (More)
DOI: 10.1152/ajpgi.00282.2013

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