Microbiota of severe early childhood caries before and after therapy.

  title={Microbiota of severe early childhood caries before and after therapy.},
  author={Anne C. R. Tanner and Ralph L Kent and Pernilla Lif Holgerson and Christopher V. Hughes and Cheen Y. Loo and Eleni Kanasi and Natalia I. Chalmers and Ingegerd Johansson},
  journal={Journal of dental research},
  volume={90 11},
Severe early childhood caries (ECC) is difficult to treat successfully. This study aimed to characterize the microbiota of severe ECC and evaluate whether baseline or follow-up microbiotas are associated with new lesions post-treatment. Plaque samples from 2- to 6-year-old children were analyzed by a 16S rRNA-based microarray and by PCR for selected taxa. Severe-ECC children were monitored for 12 months post-therapy. By microarray, species associated with severe-ECC (n = 53) compared with… CONTINUE READING
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